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Third, intestinal K-cells and pancreatic islet cells, including -cells, may also contribute to pasireotide-induced hyperglycemia 17,21,42

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Transcriptome sequencing of esr1-1 revealed altered expression of several genes involved in responses to biotic and abiotic stresses and hormone signaling pathways (Thatcher et al., 2015)

Materials and methods A systematic search was conducted in the international scientific databases, including PubMed, Embase, Web of Science, Scopus and Cochrane Central Library, for relevant studies published up to September 2021

Methionine and cysteine residues are oxidized by dissolved oxygen or peroxides, altering the peptide's three-dimensional structure and reducing receptor-binding affinity