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Glutamate cysteine ligase (GCL) catalyzes ligation of cysteine and glutamate forming -glutamylcysteine (-GC)

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A Nature Aging review emphasizes that NAD-targeted interventions are biologically interesting, but that more large-scale, long-term studies are still needed regarding optimal dosage, safety, and individual response differences

Bonina FP, Arenare L, Palagiano F, Saija A, Nava F, Trombetta D, de Caprariis P

A recent study [3,189] has found that there exists unique mitochondrial dysfunction in patients with ASD