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Glutathione, when given intravenously or intramuscularly, has a much shorter half-lifeminutes to hoursrequiring different timing strategies for maximum benefit

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It can also donate electrons to other unstable compounds, contributing to their neutralization and preventing damage

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Ideally, ECTRs in VPA intoxications should be investigated in a controlled clinical trial setting, but this is difficult to plan/perform since the overall occurrence of VPA intoxications per center will be limited to few cases