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By being custom-made, "[compounded drugs] can be risky for patients, as unapproved versions do not undergo FDA's review for safety, effectiveness and quality before they are marketed," the issue said

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The GLP-1RAs used in the other trials, including liraglutide, semaglutide, dulaglutide, and albiglutide, are all analogous to human GLP-1

However, having established that CsPT3 can actively convert apigenin to 6-PA and 6-GA, propitious biotechnology options are now available for their synthesis