Costanza Alciati, a pharma analyst at GlobalData, told BioSpace in an email that GLP-1s will definitely dominate the market in the near future, but new entrants into the space are already looking for the next drug class that could revolutionize the space. Companies taking an alternative approach are forecast to capture only a very small portion of the obesity marketroughly 6.3%across the seven major markets (U.S., France, Germany, Italy, Spain, UK and Japan) by the end of 2031, according to Sara Reci, a senior analyst at GlobalData
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Scientific Research Review SURPASS Clinical Trial Program (Type 2 Diabetes) The SURPASS program comprised phase III trials evaluating tirzepatide 5, 10, and 15 mg once weekly in patients with type 2 diabetes: SURPASS-1 (monotherapy, n=478): Tirzepatide reduced HbA1c by 1.87% (5 mg), 1.89% (10 mg), and 2.07% (15 mg) vs
In people, diets high in fermentable fiber are associated with higher GLP-1, but researchers are still working out how much of that runs through SCFA receptors and how much through other routes