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MAPK is a key transmitter of signals from the cell surface to the nucleus and can be activated by factors such as cytokines, hormones, stressors and others to regulate cell growth, differentiation, inflammation and other physiological and pathological processes (92)

Many patients stay on treatment for several months to a year

We acknowledge the financial support from the Rappaport Family Research Institute in the Medical Sciences and from the Clinical Research Institute at Rambam Health Care Campus (CRIR).