For instance, in June 2024, a recent study by the National Library of Medicine, Secular Trends in Diabetes in India (STRiDE-I), revealed a concerning rise in type 2 diabetes (T2DM) prevalence among younger individuals (ages 2039) in southern India
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2 , 5 , 8 , 9 , 10 Classically, in the presence of T3, conformational changes in the ligand-binding domain lead to the recruitment of coactivators, including CREB binding protein (CBP)/p300 and steroid receptor coactivator 1 (SRC1), promoting gene transcription (Figure 1)