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Glutathione is involved in various important liver detoxification processes, amino-acid transport, production of coenzymes, and the recycling of vitamins C and E

Heart failure in patients is associated with downregulation of mitochondrial quality control genes

95% CI, 0.15 to 0.08

63 In a large-scale real-world study, the use of GLP-1 receptor agonists in patients with T2DM was also shown to increase the risk of intestinal obstruction compared to sodiumglucose cotransporter-2 (SGLT-2) inhibitors

The evidence was found to be reasonably robust, adequately addressing this safety concern commonly associated with GLP-1-based therapies