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The latest EUGOGO guidelines recommend a 6-month selenium supplementation for patients with mild and active TED of recent onset, because it improves eye manifestations and prevents progression to more severe forms [90]

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Lipid deposition in skeletal muscle or in adipose tissue is in turn is a driver of chronic inflammation [54, 55], which is known to be a cause of mitochondrial dysfunction [44]

Consequently, research teams can develop repeatable procedures that support scientific consistency, organized documentation, and dependable analytical practices