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No alternatives to PZQ are currently available and few drugs or vaccines are in the clinical pipeline for schistosomiasis treatment 6,7,8

Ethics declarations Conflict of interest The authors declare that they have no conflict of interest

Many studies suggest that small, polar molecules may be able to bypass the bloodbrain barrier with nasal delivery, as the interface between the nasal cavity and brain is considered a potential point of vulnerability in the bloodbrain barrier

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How to Use Take an appropriate amount and absorb it evenly into the skin