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Description Overview 5-Amino-1MQ is a selective NNMT inhibitor that elevates cellular NAD+ and SAM to enhance mitochondrial function, fat oxidation, insulin sensitivity, and overall metabolic efficiency, with preclinical data indicating preferential visceral fat loss and a favorable safety profile

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Judson et al., 2009, 2011

FDA did not evaluate Crohns disease, celiac disease, or tendonitis under the vote question because the nomination lacked sufficient information and the agency did not identify suitable clinical studies in those populations

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