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Many researchers report increased range of motion and reduced joint stiffness within the first few weeks of administration

Additionally, the pQCT data hinted that the observed increase in cortical BMC might have originated from an increase in the cross-sectional area of the bone

IGF-1 treatment: future and limitations The FDA approved the use of rhIGF-1 (Mecasermin, Increlex) for treatment of severe primary IGF-1 deficiency in 2003

doi: 10.1007/s12035-016-0369-2 54 ChenZJiangRChenMZhengJChenMBraidyNet al

The key distinction is selectivity: GHRP-6 and GHRP-2 significantly elevate cortisol, ACTH, and prolactin alongside GH