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Sparse whole-genome sequencing identifies two loci for major depressive disorder

Transgenic murine models for cognition Beyond chemical lesion models (scopolamine, 192-IgG-saporin), cognitive research has an arsenal of genetically modified strains that reproduce specific cognitive phenotypes: Alzheimer models 3xTg-AD (LaFerla): triple transgenic APP Swedish, PS1 M146V, tau P301L

Warner et al., 2004

Thiamine and diabetes Experimental evidence suggests that thiamine transport maybe abnormal in diabetes.In experimental diabetes, these was diminished intestinal absorption of thiamine and TMP

While some studies suggest potential benefits, more extensive research is needed to understand its efficacy and safety profile fully