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The rest mentioned above are capable of increasing the permeability of the gut and blood-brain barrier, contributing towards maldigestion and gastrointestinal problems , promoting neurological symptoms, and facilitating DNA and cellular damage

muciniphila has attracted attention as a next-generation probiotic because of its associations with metabolic health, gut barrier integrity, and anti-inflammatory effects [3], making it a strong candidate as a potent therapeutic intervention for a range of chronic diseases from obesity to dementia

This finding suggests that the supplementation of Se effectively reduces Tau phosphorylation and deposition, alleviates the formation of pathological spheroids, and prevents axonal degeneration in diverse neuronal populations in vivo

Inhibitors of the sodium-glucose cotransporter 2 (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1 RA) have been studied and trialled in type 2 diabetes with an overwhelming body of evidence supporting their use in type 2 diabetes [10]