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One such study with semaglutide (generic drug name for Wegovy) found that on discontinuation of the medication, patients regained about two-thirds of their prior weight loss in just a year.* 2/3 of lost weight regained within one year of stopping semaglutide 2/3 of lost weight regained within one year of stopping semaglutide A similar study tested deprescribing of tirzepatide (generic drug name for Zepbound)

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Here, we confirmed that CCK secretion is higher from ob / ob compared to lean mouse islets 5 and show that non-diabetic human islets secrete small amounts of active, sulfated CCK peptide (Fig