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doi:10.37765/ajmc.2025.89778

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Melanoma In a study of melanoma, it was found that miR-137 negatively regulates ferroptosis by directly acting on the glutamine transporter SLC1A5 in melanoma cells, while knockdown of miR-137 promotes ferroptosis 53

These findings align with a model in which ERR activation restores mitochondrial oxidative capacity and lipid flux in hepatocytes, contributing to reversal of steatotic features