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For patients with Long COVID or ME/CFS, practitioners often recommend starting with a smaller dose (e.g., 1/4 or 1/2 scoop) to assess tolerance, as rapid detoxification can sometimes cause a temporary exacerbation of symptoms (a Herxheimer reaction) as toxins are mobilized

It has been reported both in vitro and in vivo that naringin decreases the production of inflammatory mediators and proinflammatory cytokines and attenuates clinical symptom severity [70, 71]

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Perlmutter: Most of our MS patients are on glutathione for purposes of brain protection

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