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A natural complex (Gly-His-Lys + Cu 2+ ) found in plasma, saliva, and urine, known in dermatology for promoting collagen synthesis , fibroblast proliferation , ECM remodeling , and dermal healing

In addition, the high expression of NRF2 enhances the expression of downstream SOD1, an important antioxidant enzyme that plays a crucial role in protecting cells from oxidative damage [36]

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While not directly measuring iron content, diffusion tensor imaging parameters show alterations in the SN of PD patients that may reflect microstructural changes associated with ferroptosis-induced cell death

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