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In conclusion, probiotics promote the activation of immune cells in the host gastric mucosa, increase the secretion of cytokines such as IL-10 and IgA, and enhance the host immune defense function

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It has been demonstrated that tPA and fibrin trigger elevation of proinflammatory and procoagulant proteins and reduce tight junction proteins in the endothelial cells

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doi:10.1007/s00125-003-1103-y Christensen M, Vedtofte L, Holst JJ, Vilsbll T, Knop FK