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Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have demonstrated clinically significant cardiovascular and kidney benefits in individuals with type 2 diabetes (T2D) and cardiovascular benefits in those with obesity and atherosclerotic cardiovascular disease at baseline 6,7

Adv Sci 12(4)

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The immune protection of embryo by kynurenines is further supported by the observations that with progressing pregnancy, IDO (indoleamine-2,3-dioxygenase, the enzyme initiating tryptophan catabolism) expression is up-regulated by inflammatory cytokines including its most potent stimulant, interferon gamma, and immunosuppressive kynurenines are generated [12]

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