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A pair of identical twins discordant for myalgic encephalomyelitis/chronic fatigue syndrome differ in physiological parameters and gut microbiome composition

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Here, the researchers investigate the association of the MTHFR C677T polymorphism with CHD in unpublished datasets that have analyzed this polymorphism incidentally during other genetic studies

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In addition to the observed increase in mitochondrial fragmentation, the overexpression of FIS1 has also been demonstrated to result in mitochondrial dysfunction and an increase in autophagosome formation (Twig et al., 2008)