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The table says a history of myocardial infarction, stroke, heart failure, or atherosclerotic cardiovascular disease may lower the BMI threshold, and the narrative adds that a provider may recommend therapy beyond standard criteria when cardiovascular risk factors or metabolic complications warrant it

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Emily Field, head of European pharmaceuticals research at Barclays, said the weight loss market was likely to grow more "fragmented" over time as pharmaceutical companies target different segments, noting that treatments to counter muscle loss could be a good way to "differentiate." However, she noted that a company of Zealand Pharma's size and scope would struggle to do so alone