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This complex subsequently activates caspase 1 (CASP1), which cleaves pro-IL1B, pro-IL18, and GSDMD

Metabolic profiling by Seahorse assay suggested that melatonin treated ILC2s exhibited decreased rates of basal respiration ( Figure 5P ), decreased spare respiratory capacity ( Figure 5Q ), and both reduced active rates of glycolysis ( Figure 5R ) as well as reduced glycolytic capacity ( Figure 5S )

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Parker-Athill and Tan, 2010