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The monthly cost is the number patients actually care about

[13] [14] Systematic reviews and meta-analyses of GLP-1 receptor agonists have generally shown a neutral effect on heart failure hospitalisation, which is reassuring

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[1] [4] Patients should be alert to warning signs such as severe upper abdominal pain (especially if radiating to the back), jaundice, dark urine, or pale stools, and seek urgent medical attention if these occur

In evolutionary terms, fat storage offers survival value , while excess muscle increases energy expenditure