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The aberrant neurotransmission is associated with several structural and functional changes in the brain and other encephalic structures, as it has been observed that patients with BD display abnormalities in neural circuitries supporting emotion processing, emotion regulation and reward processing [36]
46 In one study that included 109 university students, higher sleep satisfaction was more closely aligned with positive mood, sense of well-being, and life satisfaction than objective measures of sleep quality
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Research has confirmed that the COVID-19 mortality rate sharply increases among seniors, with the majority of deaths reported among those aged 70 years and older 3 , and among individuals who have pre-existing conditions such as frailty, obesity, diabetes and hypertension independent of age 3
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