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Enteroendocrine cells (EEC) have been studied extensively for their ability to regulate gastrointestinal motility, secretion, and insulin release by release of peptide hormones
doi: 10.3389/fendo.2020.00178
Once bound to the IGF-1 receptor 3 (IGF-1R), it triggers key anabolic pathways such as Akt/mTOR , stimulating protein synthesis, cellular growth, and repair
A few small-scale studies have explored whether weight loss achieved through GLP-1 therapy might indirectly benefit patients with rheumatoid arthritis
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