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doi: 10.1016/j.ejphar.2011.10.015 104
Studies showed that increased TMAO level induced the activation of NF-kappa B (NF-B) pathway and increased the expression of pro-inflammatory genes including inflammatory cytokines, adhesion molecules and chemokines (Seldin et al., 2016
Its effects are not just limited to one area and may also involve the brain and nerves, helping the body respond better to stress and injury
Partial existing research announced that hyperuricemia could act as an inhibitory factor for periodontitis, while other scholars presented that a high uric acid (UA) level was more likely to aggravate inflammatory immune response and lead to more serious tissue destruction
F., Paula Ravagnani, F
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