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Procedures The trial consisted of a first visit for participants screening and familiarization with the set-up, instructions and equipment, followed by two administration periods lasting 4 weeks

In some embodiments, the amount of thermoreversible polymer (e.g., pluronic F127) in any formulation described herein is about 23% of the total weight of the formulation

Clinically, BPC-157 is often used by athletes and patients recovering from surgery or chronic injuries due to its capacity to modulate the nitric oxide (NO) system, protect endothelial function, and reduce pro-inflammatory cytokines

Ethics statement The study was approved by the Ethics Committee of the Qinhuangdao Integrated Traditional Chinese and Western Medicine Hospital (Approval No.: KY202403020041)

NMN supplementation at 250-1,000 mg daily increased whole blood NAD+ by 75% to six-fold in various trials [13]