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A 2024 pilot study in interstitial cystitis represents one of few published human-cohort efforts (PMID 39325560), though it is small and single-centre

Some patients have had previous nerve blocks or Botox injections by neurologists or pain doctors and have not found relief

Update in: Cochrane Database Syst Rev

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This has occured when people are desperately ill and havent the strength or the inclination to battle with their GP for correct treatment