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In the analysis depending on the preceding drugs, annual eGFR decline (mL/min/1.73 m 2 /year) significantly changed from 2.3 2.5 to 1.7 2.3 in SGLT2i-preceding group ( p = 0.001), whereas that changed from 2.0 2.9 to 1.5 2.4 in GLP1Ra-preceding group ( p = 0.06) (Table 2B)

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Similarly, a meta-analysis of 24 RCTs by Shrime et al

It also slows digestion and increases fullness, causing decreased appetite and weight loss