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Multiple rodent models of PCOS, capitalizing mainly on the impact of androgen excess at different developmental windows, with variable penetrance in terms of reproductive and metabolic impairment, have been used in translational studies, in order to capture the phenotypic heterogeneity of the syndrome 38

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These findings highlight the importance of maintaining continuous GLP-1 treatment to sustain cardiovascular benefits and indicate that strategies to reduce treatment discontinuity should be developed to maximize the cardioprotective effects of GLP-1s

Mammalian SWI/SNF chromatin remodeling complexes and cancer: mechanistic insights gained from human genomics

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