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Moreover, while OCCC show intrinsic resistance to conventional platinum-based chemotherapy, OSC exhibit at first sensitiveness to platinum-based chemotherapy, though the majority of cases develop chemoresistance during the course of treatments 33,34

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On the other hand, TGF-, together with other molecules such as IL-4, are considered inducers of regulatory T cells (Tregs), capable of blocking the antitumor effect of the immune system

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Coaching support is integrated into the platform alongside clinical care