For acute injuries, the traditional RICE protocol (rest, ice, compression, elevation) emphasizes immediate cold application during the first 48 hours when inflammatory processes are most active
C.Snchez-CrdenasC.BakerM.et al (2016)
Critically, GHK-Cu delivers copper as cofactor for lysyl oxidase and lysyl hydroxylase, copper-dependent enzymes essential for collagen cross-linking and stability
This not only includes collagen but also glycosaminoglycans (GAGs), which are critical for maintaining skin structure and hydration
Conclusion Overall, the treatment landscape for Thalassemia is rapidly evolving, with gene therapies and other novel agents providing new hope for reducing transfusion requirements and managing complications like iron overload for these patients