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FN receptors are located in every tissue that originates from the three primary germ layers and are therefore considered to modulate embryogenic cellular migration and anchoring (24), which suggested the FN signaling may mediate the cellular-ECM signal transduction that may, in turn, modulate LOX secretion

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First, reduce exposure to environmental toxins, pollutants, and chemicals whenever possible

This includes assessment of tissue resilience, inflammatory signaling, and regenerative capacity at the cellular level

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