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Research in mice suggested that IGF1-related mitochondrial protection might also play a role 10

Citrate is found in supplements as an additive, in food as a preservative, and is sometimes added as citric acid or sodium citrate

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It promotes the conversion of liver glycogen to glucose and increases gluconeogenesis, as well as enhancing fat breakdown to provide energy

108,109 Members of the subfamily II of the SLC30 proteins (ZnT2, ZnT3, ZnT4, and ZnT8) play a major role in secretory tissues, with ZnT3 involved in neurotransmission, ZnT8 in insulin storage, ZnT4 in prostate secretion, and ZnT2 in lactation