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When a DPP-4 inhibitor is added to a sulfonylurea regimen, the sulfonylurea dose may need to be reduced Pioglitazone offers similar glycaemic efficacy to gliptins but is associated with fluid retention and fracture risk DPP-4 inhibitors are generally considered weight-neutral , which is an advantage over sulfonylureas and insulin

If you are a Kaiser member, start with your PCP, get into the weight management program, and be proactive about documentation

Rovira Guasch R, Ravents Estell A, Mart-Henneberg R, Closa Monasterolo R

It was developed as a structurally defined research tool to investigate cytoprotective and anti-inflammatory signalling mechanisms independent of red blood cell production

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