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Research from the STEP clinical trial program demonstrated that weight loss outcomes were dose-dependent, with significantly greater reductions at higher doses

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In clinical trials, retatrutide produced greater weight loss (~24-29%) compared to semaglutide (~15-17%)

Cells were grown at 37 C to an optical density at 600 nm (OD 600 ) of 0.70.8 in lysogeny broth (LPS solution LB-05) medium, and then 0.5 mM of isopropyl-1-thio--D-galactopyranoside (LPS solution IPTG025) was added