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However, data on depot-specific expression of 11-HSD1 remain inconsistent [147]

Nutrient sensing occurs in the stomach and duodenum and is signaled to the brain through neural pathways, but especially through the release of gut peptides, which was shown in some studies to be correlated with symptoms in FD and gastroparesis

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There have been small phase one and phase two trials on rectal BPC-157 enemas, which showed no adverse effects, but the data is limited, and most of it comes from one research group, with some replication by Chinese groups 6m1s