Formation and Mechanism Long-term UV exposure triggers melanin production to prevent sun damage Oxidative stress due to heat damages skin cells Appearance Face, hands, arms, neck, and feet Distinguishing Features Uneven tanning of the body (Appears only on the exposed areas Freckles or sun spots Often appears with aging Uneven Skin Tone In uneven skin tone, there are no defined dark spots, but general skin dullness or patchy pigmentation
References Bozkurt B, Ahmad T, Alexander K, et al
Sign in to add to wishlist More Details Specifications Full Ingredient List Disclaimer Description Product highlights: Helps reduce melasma, sun spots, age spots and acne scars Prevents the future development of freckles and hyperpigmentation Reduces the appearance of sun damage Does not irritate the skin or cause prolonged erythema High arbutin and tranexamic acid content, alongside antioxidant glutathione How to use: After cleansing and applying toner, apply to targeted areas of pigmentation once daily
This protocol rapidly induced marked functional disability, in particular, a difficulty with maintaining body balance while rearing, an inability of the right forelimb to react (and thereby cuprizone-rats react only with one or no forelimb), and severely affected various brain areas [31]
Estimated materials for a 420 week research protocol Plan based on an 820 week weekly titration protocol
