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It is of particular note that trophoblasts begin to invade the endometrium (endoglandular trophoblast) already at the time of implantation, enabling nutrition of the embryo before the perfusion of the placenta with maternal blood [33]

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A 2024 meta-analysis of 17 studies (402 UC and 362 CD) [70] showed that the percentage of circulating Treg cells was significantly reduced and the inhibitory function of circulating Treg cells was impaired in patients with active IBD and healthy controls, and the proportion of Treg cells in the inflammatory area of the intestine was higher than that in the non-inflammatory area