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499 This clinical trial is based on a proposed mechanism that sodium selenate acts as a specific agonist for PP2A, one of the implicated phosphatases in regulating tau protein phosphorylation

10.1080/15548627.2017.1291113 Autophagy 273 YamashitaS

When you swallow an oral supplement, the active compounds have to survive stomach acid, get absorbed through the intestinal wall, and pass through the liver's first-pass metabolism before reaching systemic circulation