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Wade, J

Some people expect to be very tempted, but find that they simply no longer have much interest in certain foods that used to be irresistible to them

During illness, your needs increase due to: Fever can increase insensible fluid losses and may increase fluid needs (often estimated around 10% per 1C) Respiratory symptoms causing moisture loss through breathing Reduced thirst sensation from GLP-1 effects Potential vomiting or diarrhea Adequate hydration during illness helps thin mucus secretions, supports immune function, maintains blood pressure, and prevents medication-related complications

These studies contribute to understanding both efficacy-related aspects and potential risks before the first administration in humans