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That receptor-level mechanism is why dosage does not follow a simple linear dose-response curve and why higher doses do not produce proportionally greater fat loss
Additionally, cocaine induces apoptosis in cerebral vascular smooth muscle cells, contributing to vasoconstriction and ischemia, resulting in significant neurological damage ( 3.2 Neurological damage and psychiatric symptoms The neurological effects of cocaine include diffuse leukoencephalopathy, which is characterized by vasospasms, cerebral ischemia, and posterior reversible leukoencephalopathy (Rowbotham and Lowenstein, 1990
Scientific Context| One compound that has attracted attention in metabolic and neurological research is Vitamin B12 (commonly cyanocobalamin or methylcobalamin), an essential nutrient involved in red blood cell formation, DNA synthesis, and energy metabolism
Nashawi H, Gustafson TJ, Mietlicki-Baase EG
Endocrinology 158 , 12311251 (2017)
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