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Below is an example of introducing non natural amino acids: R1-NH 2 + C 10 H 10 N 2 O 2 -OH C 10 H 10 N 2 O 2 -R1 + H 2 O It should be noted that due to the different structures of the amino acid side chain group R1, the reaction conditions, solvents, reagents, etc

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This estrogen loss is especially observed when women approach peri- and postmenopause [9] and has a profound impact on dermal health and affects almost all organ systems, which has an overall negative influence on womens quality of life (QOL) [10]

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