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10 th ed: John Wiley & Sons, Inc

However, these drugs have not been transformed into clinical applications to benefit patients with kidney diseases[165]

A shift in carbon flux from -oxidation to the riboflavin biosynthetic pathway was proved by a twofold increase in ADE1 , RIB1 , and RIB5 protein synthesis, and in gene expression of gluconeogenesis and pentose phosphate cycles, but it was observed that the downregulation of pathways were related to carbon source assimilation, energy generation, and glycolysis at the riboflavin-producing phase (Table 3

GHK-Cu, short for Gly-His-Lys-Copper, is a small peptide naturally present in the human body

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