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N Engl J Med (2019) 380(20):194153

In the human body, it is produced in the liver to help defend the body against toxic substances like free radicals, peroxides, and toxic metals

These findings suggest a correlation between the progressive worsening of moderatesevere AD and vitamin C decreased levels (93)

PMCID: PMC5332963

Taken together, these observations suggest that except in vitamin B 12 deficiency (which only responds to cyanocobalamin treatment because of the inactivation of methionine synthase), folate treatment should be the most adequate therapy to reverse hyperhomocysteinemia detected both under basal conditions and after an oral methionine load