does semaglutide help with thyroid issues JEFF ROSE, CFP® | Ozempic is facing a $2 billion lawsuit and the cancer headline is actually the least of Novo Nordisk's problems. Over 3,500 people Can You Take Semaglutide While

Unlike the VLED, semaglutide did not appear to downregulate levels of satiety hormones such as PYY and amylin, and upregulated CCK levels

The SELECT trial showed semaglutide produces a 20% reduction in major cardiovascular events in patients with obesity and established heart disease

found that fast escalation to 8 mg produced GI adverse events in 50% of participants, compared to roughly 35% with gradual titration (Rosenstock et al., Lancet, 2023)

These effects are often dose-related and may lessen as the body adjusts to the medication

Other common adverse effects include diarrhea, constipation, dyspepsia, abdominal pain, and decreased appetite [47]