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The goal of these detoxification pathways is to create molecules that the body can easily get rid of (urine, feces, sweat).[ref] CYP450 Genetic Variants: Genetic variants in CYP450 enzymes can significantly impact how an individual metabolizes various toxicants, medications, and substances produced within the body

intermittent treatment with senolytics have conclusively reduced senescent cell burden in peripheral tissues (fat, lung, kidney, pancreas, cartilage, and muscle), improved pathologies in these tissues, and extended healthspan and lifespan (45, 46, 100-103)

What is the immunogenicity concern

use is typically under a licensed clinicians supervision for research or compounded medical use