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5.4 Herbal medicines and natural bioactive compounds Herbal medicines and natural compounds have demonstrated significant therapeutic potential in the management of EDC due to their multi-component, multi-target, and multi-pathway synergistic effects

However, avoid mega-dosing individual supplements without medical guidance, as excessive intake of certain nutrients (particularly fat-soluble vitamins like vitamin A) can paradoxically contribute to hair loss or other adverse effects

Cukierman-Yaffe, T., et al

Although GSH supplementation restored mTORC1 signaling and the ISR during cystine starvation, inhibition of GGT, the key enzyme responsible for ecto-degradation of GSH, abolished the rescue effects of GSH (Fig