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The RDA The recommended dietary allowance (RDA) for thiamin, revised in 1998 by the Food and Nutrition Board of the Institute of Medicine, was based on the prevention of deficiency in generally healthy individuals (37

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Results Study design and patient characteristics To identify metabolic signatures associated with shunt responsiveness, we performed a two-stage metabolomics study comprising a discovery screen (semi-targeted) followed by targeted evaluation ( Figure 1 )